Role of Procalcitonin, C-reactive Protein and Total Leucocyte Count in Suspected Cases of Sepsis

Background: Sepsis is a life-threatening infection, responsible for tremendous morbidity, mortality and healthcare expenditure worldwide. characterized by non-specific symptoms clinical diagnosis remains difficult. C Reactive protein (CRP) procalcitonin (PCT) are now days used as surrogate markers of sepsis. Aim: To determine PCT levels in patients with suspected sepsis its correlation CRP total leucocyte count (TLC). Material & Methods: The retrospective study was conducted tertiary care hospital India. Adults (> 18 years) admitted to Intensive unit the during period, fulfilling ACCP criterion were included study. Data collected using laboratory software maintaining confidentiality. Results: comprised 190 patients. Patients divided into four groups based on values severity Out patients, positive 135 TLC distributed their studied. For between 2-10ng/ml, >10ng/ml showed statistically significant p value <0.05, whereas poor. Conclusion Procalcitonin along better diagnostic tool but context Due lack an ideal isolated marker, our mandates multidisciplinary approach Keywords: Sepsis, Procalcitonin, reactive protein, Total count, Culture